Despite the many alternative flavors of NoSQL databases that have caught the attention of developers over the years, relational databases remain the de facto standard for storing and retrieving digital information. Every technology worker from the back-office IT personnel to the modern Web developer has been trained to use, manage, and query relational databases …

In 2021, the US Department of Defense spent $142 billion on procurement and $106 billion on developing new technologies (RDT&E) — while global defense spending reached over two trillion dollars. Yet the US and its allies are potentially dangerously wrong-footed by having over-spent on legacy hardware systems (eg aircraft carriers etc) while neglecting what could be the defining battlefield of the future …

As new tooling, entrepreneurial accessibility and AI continue to unlock evolution’s algorithms, programmable biology is moving from vision to reality at increasing speed …

As humans age the chances of dying from specific diseases (cancer, coronary, neurological, etc.) increase, where the rate of aging is controlled by genetic pathways and biochemical processes conserved in evolution. Although the hallmarks of aging (including several cellular and molecular processes such as genomic instability, telomere attrition, stem cell exhaustion etc) …

Due to abnormal metabolism, certain diseased tissues, most notably solid tumors, produce an acidic extracellular microenvironment that is still little understood. Nevertheless, today all drugs in oncology are developed by R&D teams using the same classic textbook definition of tumor acidity which leads to (among other issues) poor tumor targeting and specificity …

Watch (and ask questions!) as Sander and Chad build a questionnaire (where only holders of a selected NFT collection can answer) and walk through Tableland's architecture and concretely how to use this new decentralized SQL database to store and retrieve metadata for web3 apps …

The explosion in computing resources over the last decade has made it possible for the extremely complex systems of molecular biology to be simulated in high enough fidelity to begin to produce new materials, new drugs and other important substances …

Artificial intelligence has made significant strides in recent years, particularly with the rise of generative AI and large language models (LLMs). These innovations have sparked our collective imagination, turning once fictional concepts into tangible products used by companies at scale …

Nanotechnology, core to the $200Bn value-added materials market, has for decades been heralded as one of the most promising areas of science and industry. However, we are yet to discover even 1% of what is possible in nanomaterial design …

We are excited to continue our fellowship program, which launched last year with our first four fellows by opening up the process to find the next cohort of aspiring entrepreneurial scientists who want to spend a few months inside a VC firm. The program is designed to be 6 to 9 months long, as a 4 to 6-hour-per-week engagement …

We are currently navigating an era that stands apart in the history of technological innovation. Multiple, rapidly-evolving disciplines, such as blockchain, Artificial Intelligence, web3, breakthrough engineering, and synthetic biology, are increasingly intersecting and influencing one another. This convergence is weaving a rich, complex tapestry of possibilities and challenges …

We live in a time where the boundary between science fiction and reality is rapidly blurring. Scientists have used high-power lasers to reproduce the sun’s power on Earth, satellites launched by reusable rockets have made high-speed internet ubiquitous and affordable, and new computer architectures have accelerated super-human AI capabilities and understanding …